Beta-blocker exposure in pregnancy does not increase risk for fetal cardiac anomalies after adjusting for maternal comorbidities, according to a research letter published in JAMA Internal Medicine. “Beta-blockers are the most commonly used class of medication for treating cardiac conditions in pregnant women.
Why are beta blockers contraindicated in pregnancy?
(10-14) However, beta-blockers cross the placental barrier and are associated with several adverse effects, such as delayed intrauterine growth, respiratory depression, neonatal bradycardia and hypoglycemia, particularly when treatment is started early on in the pregnancy (i.e. at 12–24 weeks).
Which beta-blocker is best for pregnancy?
There is a general consensus that labetalol is safer than other β-blockers during pregnancy, and this drug is rapidly becoming the first-line choice in conditions, such as chronic hypertension during pregnancy.
Do beta blockers cross the placenta?
β-Blockers are the most commonly used class of medication for treating cardiac conditions in pregnant women. Despite the common use of this class of medication, data that support its safety are limited. β-Blockers cross the placenta and potentially can cause physiological changes in the fetus.
Who should not take beta blockers?
Beta-blockers should not be prescribed if you have low blood pressure or a slow pulse, because the further reduction in heart rate can cause dizziness and lightheadedness. If you have asthma or chronic obstructive pulmonary disease (COPD), your doctor may not prescribe a beta-blocker because it may worsen symptoms.
Can beta blockers cause birth defects?
Beta-blockers used to treat hypertension during the first trimester of pregnancy don’t appear to increase the risk that babies will be born with birth defects or cardiac malformations, according to an analysis of observational data on more than 18,000 women across five Nordic countries and the United States.
What is the safest blood pressure medication during pregnancy?
Methyldopa has been used for decades to treat high blood pressure in pregnancy and it appears to be safe. Labetalol has been extensively studied and has become increasing prescribed in pregnancy. Labetalol is now commonly used as a first-line treatment choice. Nifedipine is also sometimes used in certain situations.
Can propranolol harm my baby?
Propranolol use in late pregnancy may cause the baby to have symptoms of the drug acting on its heart, blood vessels, and metabolism. Symptoms would include slowed heart rate and low blood sugar. Does taking propranolol in pregnancy cause long-term problems in behavior or learning for the baby.
Will labetalol affect my baby?
Labetalol is not thought to harm an unborn baby. But there’s a small chance that when your baby’s born the medicine can affect their blood sugar levels. For this reason your baby may be monitored for the first 24 hours to make sure everything is OK.
Is propranolol safe to take while pregnant?
Beta blockers may cause decreased placental perfusion, fetal and neonatal bradycardia, and hypoglycemia. Propranolol has been used safely to treat a variety of conditions during pregnancy, including hypertension and pheochromocytoma in the mother, and tachyarrhythmias in both the mother and fetus.
Are Beta Blockers Safe?
These drugs also increase the chances of living longer and better with heart failure. The reviewers found that different beta blockers work better for different conditions. Safety. Beta blockers are generally safe to take.
How do beta blockers cause bronchospasm?
Pulmonary Side Effects
The problem with using beta-blockers if you have lung disease is that beta receptors are also found in lung tissue. When epinephrine binds to beta receptors in the lungs, the airways relax (open). That is why you might use an EpiPen to treat a respiratory emergency.
What is tachycardia in pregnancy?
In pregnancy, heart rate (HR) increases by 25%; thus sinus tachycardia, particularly in the third trimester, is not uncommon. Ectopic beats and non‐sustained arrhythmia are encountered in more than 50% of pregnant women investigated for palpitations while sustained tachycardias are less common at around 2–3/1000.
Can you eat bananas with beta blockers?
If you are taking a beta-blocker, your health care provider may recommend that you limit your consumption of bananas and other high potassium foods including papaya, tomato, avocado and kale.
Do beta blockers shorten your life?
A large study published last month in The Journal of the American Medical Association found that beta blockers did not prolong the lives of patients – a revelation that must have left many cardiologists shaking their heads (JAMA, vol 308, p 1340).
Is it bad to take beta blockers everyday?
If you take beta-blockers regularly, you may have serious withdrawal symptoms if you suddenly stop. For some people, the side effects of beta-blockers may actually cause anxiety symptoms. You should follow up with your doctor as soon as possible if you feel like taking beta-blockers is increasing your anxiety.